PARP Protein Structure with bound ligand
DGRSCROLL Analysis
Docking Score:-9.2

Precision Starts at the Sidechain

Durdağı Research Group's Side Chain Rotation for Ligand Landing

DGRSCROLL redefines structural refinement at the molecular interface. Transform rigid docking into dynamic precision with intelligent sidechain optimization powered by genetic algorithms.

Explore DGRSCROLL in Action

Discover how our platform transforms molecular docking through advanced visualization and optimization techniques.

DGRSCROLL Molecular Analysis

Precision Molecular Docking

Advanced protein-ligand interaction modeling with dynamic sidechain optimization

Genetic Algorithm Optimization

Evolution-Driven Optimization

Genetic algorithms powering intelligent sidechain conformation search

Research Laboratory

Cutting-Edge Research

State-of-the-art computational biology research at Durdağı Lab

Molecular Interface Analysis

Interface Refinement

Detailed analysis of protein-ligand binding interfaces and interactions

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Why Choose DGRSCROLL?

In drug discovery, accuracy isn't optional—it's everything. Our platform goes beyond traditional docking limitations.

Evolution-Driven

Genetic algorithm-powered engine searches and resolves sidechain conformations that reflect true binding interactions.

Precision Docking

Move beyond static sidechains and pre-defined rotamers. See your protein as it wants to bind, not just as it was prepared.

Next-Generation

Web-based platform that transforms molecular interface refinement with intelligent optimization algorithms.

Reimagine Your Protein–Ligand Complex

Upload your protein and ligand, and watch as rigid docking turns dynamic with our three-step optimization process.

1

Upload Structure

Submit your protein and ligand structures through our intuitive web interface.

2

Optimize Sidechains

Our genetic algorithm engine dynamically optimizes sidechain conformations for optimal binding.

3

Analyze Results

Receive detailed structural analysis and refined protein-ligand complex for your research.

Because Your Protein Deserves to Breathe

Whether you're fine-tuning a lead compound, validating a docking hypothesis, or exploring novel interactions, DGRSCROLL reveals the structure as it truly wants to bind.